Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.63 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.63 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8924338 | 0.85 | CYP4A11 (0.59) | CYP4F2CYP4A11LOXL2MEN1KMT2A | |
| SCHEMBL29130655 | 0.85 | LOXL2 (0.57) | CYP4F2CYP4A11LOXL2MEN1KMT2A | |
| SCHEMBL70173 | 0.80 | CYP4F2 (0.83) | CYP4F2CYP4A11LOXL2MEN1KMT2A | |
| SCHEMBL6121831 | 0.79 | MEN1 (0.53) | MEN1KMT2ABLMCTDSP1L3MBTL1 | |
| SCHEMBL5663990 | 0.79 | CYP4A11 (0.91) | CYP4F2CYP4A11LOXL2SLC7A5FOLH1 | |
| SCHEMBL1792728 | 0.79 | CYP4A11 (0.75) | CYP4F2CYP4A11LOXL2SLC7A5FOLH1 | |
| SCHEMBL10606812 | 0.79 | CYP4A11 (0.75) | CYP4F2CYP4A11LOXL2MEN1KMT2A | |
| SCHEMBL28231008 | 0.78 | CYP4F2 (0.69) | CYP4F2CYP4A11LOXL2MEN1KMT2A | |
| SCHEMBL31752875 | 0.78 | CYP4A11 (0.69) | CYP4F2CYP4A11LOXL2MEN1KMT2A | |
| SCHEMBL18540811 | 0.77 | CYP4A11 (1.00) | CYP4F2CYP4A11LOXL2SLC7A5FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685466-A1 | 3-Heteroaliphatyle-and 3-hetero-(aryle)-aliphatyle-2(1H)-quinolone derivatives | CIBA-GEIGY AG (CH) | 1995-12-06 | — | — | EP | disclosed |