Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 9/20 | 0.52 |
| ▸ | PPARG | P37231 | 4/20 | 0.52 |
| ▸ | PPARD | Q03181 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767679 | 0.93 | PPARA (0.59) | GAAHTTTSHRPPARAPPARG | |
| SCHEMBL8768686 | 0.93 | PPARA (0.61) | GAAHTTTSHRPPARAPPARG | |
| SCHEMBL8767727 | 0.93 | PPARA (0.61) | GAAHTTTSHRPPARAPPARG | |
| SCHEMBL8767784 | 0.93 | PPARA (0.61) | GAAHTTTSHRPPARAPPARG | |
| SCHEMBL8767827 | 0.91 | GAA (0.52) | GAAHTTTSHRPPARAPPARG | |
| SCHEMBL8768099 | 0.90 | TSHR (0.52) | GAAHTTTSHRPPARAPPARG | |
| SCHEMBL8768167 | 0.88 | PPARA (0.57) | GAAHTTTSHRPPARAPPARG | |
| SCHEMBL8926283 | 0.85 | PPARA (0.68) | PPARAPPARGPPARDMAPT | |
| SCHEMBL8768931 | 0.85 | PPARA (0.52) | GAAHTTTSHRPPARAPPARG | |
| SCHEMBL8767844 | 0.85 | PPARA (0.58) | GAAHTTTSHRPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658944-A | ANTICHOLESTEROL AGENTS | THE UNIVERSITY OF SOUTH CAROLINA (US) | 1997-08-19 | — | — | US | disclosed |