Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 16/20 | 0.40 |
| ▸ | IMPDH1 | P20839 | 3/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4476507 | 0.83 | TDP1 (0.32) | IMPDH2IMPDH1 | |
| SCHEMBL14458460 | 0.82 | IMPDH2 (0.33) | IMPDH2IMPDH1 | |
| SCHEMBL2029504 | 0.82 | IMPDH2 (0.33) | IMPDH2IMPDH1 | |
| SCHEMBL21602868 | 0.81 | IMPDH2 (0.41) | IMPDH2IMPDH1ADRA1DADRA1AADRA1B | |
| SCHEMBL32689518 | 0.81 | IMPDH2 (0.41) | IMPDH2IMPDH1ADRA1DADRA1AADRA1B | |
| Methoxymethane SCHEMBL7618244 | 0.80 | IGF1R (0.33) | — | |
| SCHEMBL8923873 | 0.80 | IMPDH2 (0.32) | IMPDH2 | |
| SCHEMBL8960395 | 0.80 | ADRA1D (0.30) | ADRA1DADRA1AADRA1B | |
| SCHEMBL8924858 | 0.77 | PTGS1 (0.30) | — | |
| SCHEMBL8923275 | 0.77 | GAA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624961-A | Benzylaminoethoxybenzene derivatives, production thereof and use thereof | JAPAN TOBACCO INC. (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0693474-A1 | NOVEL BENZYLAMINOETHOXYBENZENE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Toyo Boseki Kabushiki Kaisha (JP) | 1996-01-24 | — | — | EP | disclosed |