Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.55 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.55 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | PAM | P19021 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8923376 | 1.00 | DGKA (0.59) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL8925028 | 0.98 | DGKA (0.56) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL8924745 | 0.95 | DGKA (0.51) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL31011402 | 0.92 | DGKA (0.69) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL22746298 | 0.92 | DGKA (0.69) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL23223340 | 0.92 | DGKA (0.69) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL10392579 | 0.92 | DGKA (0.69) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL31131446 | 0.92 | DGKA (0.69) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL23136981 | 0.92 | DGKA (0.69) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL22746296 | 0.92 | DGKA (0.69) | DGKAPRSS1PRSS2PRSS3NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639770-A | SUPEROXIDE INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0600092-A1 | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |