SCHEMBL8924634

SCHEMBL8924634

CC/C(C=O)=C\c1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.66
TDP1 Q9NUW8 1/20 0.64
ALDH1A1 P00352 2/20 0.55
TSHR P16473 1/20 0.55
AKR1C3 P42330 1/20 0.50
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
NR1I2 O75469 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
AKR1C1 Q04828 1/20 0.44
KDM1A O60341 1/20 0.43
RECQL P46063 1/20 0.43
HTT P42858 1/20 0.42
FBP1 P09467 1/20 0.41
CYP2A6 P11509 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL629156 1.00 LMNA (0.66) LMNATDP1ALDH1A1TSHRAKR1C3
SCHEMBL3337166 1.00 LMNA (0.66) LMNATDP1ALDH1A1TSHRAKR1C3
SCHEMBL28363417 0.86 LMNA (0.51) LMNATDP1ALDH1A1TSHRAKR1C3
SCHEMBL17444731 0.84 LMNA (0.77) LMNATDP1ALDH1A1TSHRAKR1C3
SCHEMBL20424858 0.84 LMNA (0.77) LMNATDP1ALDH1A1TSHRAKR1C3
SCHEMBL24352196 0.83 ALDH1A1 (0.61) LMNATDP1ALDH1A1TSHRAKR1C3
SCHEMBL22423775 0.82 CYP2A6 (0.46) LMNATDP1ALDH1A1TSHRAKR1C3
SCHEMBL574972 0.82 CYP2A6 (0.46) LMNATDP1ALDH1A1TSHRAKR1C3
SCHEMBL574971 0.82 CYP2A6 (0.46) LMNATDP1ALDH1A1TSHRAKR1C3
SCHEMBL113478 0.81 LMNA (0.90) LMNATDP1ALDH1A1TSHRAKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118061742-A Vehicle-mounted fragrance and preparation method thereof 广州汽车集团股份有限公司 2024-05-24 CN claimed
US-4172955-A REARRANGMENT OF A CINNAMALDEHYDE TO A PHENYLMALONDIALDEHYDE TETRAMETHYL DISACETAL EMERY INDUSTRIES, INC. (US) 1979-10-30 US claimed
EP-4665713-A1 NEMATICIDAL COMPOUNDS, THEIR COMPOSITION AND USE THEREOF Bhukhanwala, Komal (IN) 2025-12-24 EP disclosed
WO-2024171230-A1 NEMATICIDAL COMPOUNDS, THEIR COMPOSITION AND USE THEREOF BHUKHANWALA KOMAL (IN) 2024-08-22 WO disclosed
CN-118061742-A Vehicle-mounted fragrance and preparation method thereof 广州汽车集团股份有限公司 2024-05-24 CN disclosed
CN-118061742-A Vehicle-mounted fragrance and preparation method thereof 广州汽车集团股份有限公司 2024-05-24 CN disclosed
US-11891703-B2 Corrosion inhibition package DORF KETAL CHEMICALS FZE (AE) 2024-02-06 US disclosed
EP-3532459-B1 LSD1 INHIBITORS AND MEDICAL USES THEREOF CONSTELLATION PHARMACEUTICALS INC (US) 2023-08-02 EP disclosed
EP-3532459-B1 LSD1 INHIBITORS AND MEDICAL USES THEREOF CONSTELLATION PHARMACEUTICALS INC (US) 2023-08-02 EP disclosed
US-11547695-B2 LSD1 inhibitors and medical uses thereof CONSTELLATION PHARMACEUTICALS, INC. (US) 2023-01-10 US disclosed
US-11547695-B2 LSD1 inhibitors and medical uses thereof CONSTELLATION PHARMACEUTICALS, INC. (US) 2023-01-10 US disclosed
US-4520176-A DILUENT, DURABLE PRESS RESIN CONTAINING AN AMINOPLAST AND AN ALOEHYDE SWS SILICONES CORPORATION (US) 1985-05-28 US disclosed
EP-0107799-A1 Durable press resin compositions SWS Silicones Corporation (US) 1984-05-09 EP disclosed
EP-0017893-B1 PROCESS FOR THE PREPARATION OF HETEROCYCLIC TERTIARY ARALKYL AMINES BASF Aktiengesellschaft (DE) 1982-03-24 EP disclosed
US-4283534-A Reductive alkylation of nitrogen heterocycles BASF AKTIENGESELLSCHAFT (DE) 1981-08-11 US disclosed
US-4237306-A ELECTROPHILIC REACTIONS WITH ALKYL ARYL KETONES TO PRODUCE METHYL ARYL ALKANOATES EMERY INDUSTRIES, INC. (US) 1980-12-02 US disclosed
EP-0017893-A1 Process for the preparation of heterocyclic tertiary aralkyl amines BASF Aktiengesellschaft (DE) 1980-10-29 EP disclosed
US-4172955-A REARRANGMENT OF A CINNAMALDEHYDE TO A PHENYLMALONDIALDEHYDE TETRAMETHYL DISACETAL EMERY INDUSTRIES, INC. (US) 1979-10-30 US disclosed
US-4087549-A Sulphonic acid containing indenyl derivatives MERCK & CO., INC. (US) 1978-05-02 US disclosed
US-4067823-A Thallium(III) reagents supported on montmorillonite clay minerals and oxythallation processes for utilizing same EMERY INDUSTRIES, INC. (US) 1978-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11547695-B2 LSD1 inhibitors and medical uses thereof KDM1B, KDM1A, KDM2A LMNA 1502/4885TDP1 490/4885ALDH1A1 163/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.