Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | AGER | Q15109 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ASPH | Q12797 | 2/20 | 0.38 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10002474 | 0.81 | ADORA3 (0.32) | ALDH1A1TSHRLMNA | |
| SCHEMBL2519472 | 0.78 | KDM4E (0.41) | KDM4EMAPTALDH1A1L3MBTL1TSHR | |
| SCHEMBL4413036 | 0.78 | KDM4E (0.41) | KDM4EMAPTALDH1A1L3MBTL1TSHR | |
| SCHEMBL8924999 | 0.77 | KDM4E (0.46) | KDM4EMAPTALDH1A1L3MBTL1TSHR | |
| SCHEMBL8923636 | 0.72 | BRD4 (0.46) | KDM4EMAPTALDH1A1L3MBTL1ALOX15 | |
| SCHEMBL8923739 | 0.72 | KDM4E (0.36) | KDM4EMAPTALDH1A1L3MBTL1TSHR | |
| SCHEMBL69939 | 0.70 | KDM4E (0.54) | KDM4EMAPTALDH1A1L3MBTL1TSHR | |
| SCHEMBL9098715 | 0.70 | NAPRT (0.33) | KDM4EL3MBTL1NAPRTLMNAP4HTM | |
| SCHEMBL3715622 | 0.69 | POLB (0.43) | KDM4EALDH1A1L3MBTL1ALOX15KMT2A | |
| SCHEMBL269904 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639770-A | SUPEROXIDE INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0600092-A1 | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |