Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | AGER | Q15109 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ASPH | Q12797 | 2/20 | 0.38 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2519472 | 0.78 | KDM4E (0.41) | KDM4EMAPTALDH1A1L3MBTL1TSHR | |
| SCHEMBL8924724 | 0.78 | KDM4E (0.41) | KDM4EMAPTALDH1A1L3MBTL1TSHR | |
| SCHEMBL9098715 | 0.78 | NAPRT (0.33) | KDM4EL3MBTL1NAPRTLMNAP4HTM | |
| SCHEMBL6198008 | 0.78 | KDM4E (0.36) | KDM4EL3MBTL1MYCNAPRTLMNA | |
| SCHEMBL8924999 | 0.77 | KDM4E (0.46) | KDM4EMAPTALDH1A1L3MBTL1TSHR | |
| SCHEMBL7085581 | 0.77 | NAPRT (0.42) | KDM4EMAPTALDH1A1L3MBTL1TDP1 | |
| SCHEMBL8923739 | 0.72 | KDM4E (0.36) | KDM4EMAPTALDH1A1L3MBTL1TSHR | |
| SCHEMBL9158798 | 0.70 | TSHR (0.35) | ALDH1A1TSHRALOX15CYP1A2NAPRT | |
| SCHEMBL69939 | 0.70 | KDM4E (0.54) | KDM4EMAPTALDH1A1L3MBTL1TSHR | |
| SCHEMBL6345905 | 0.68 | KDM4E (0.52) | KDM4EMAPTALDH1A1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8642790-B2 | Process for preparing 5-hydroxymethylfurfural via 5-acyloxymethylfurfural as an intermediate | EVONIK DEGUSSA GMBH (DE) | 2014-02-04 | — | — | US | disclosed |
| EP-2010188-A2 | CHROMIUM COMPLEXES | Mandrillus Pharma, LLC (US) | 2009-01-07 | — | — | EP | disclosed |
| US-20080200698-A1 | PROCESS FOR PREPARING 5-HYDROXYMETHYLFURFURAL VIA 5-ACYLOXYMETHYLFURFURAL AS AN INTERMEDIATE | EVONIK DEGUSSA GMBH (DE) | 2008-08-21 | — | — | US | disclosed |
| WO-2007127867-A2 | CHROMIUM COMPLEXES | MANDRILLUS PHARMA, LLC (US) | 2007-11-08 | — | — | WO | disclosed |
| US-20070254864-A1 | CHROMIUM COMPLEXES | MANDRILLUS PHARMA, LLC (US) | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200698-A1 | PROCESS FOR PREPARING 5-HYDROXYMETHYLFURFURAL VIA 5-ACYLOXYMETHYLFURFURAL AS AN INTERMEDIATE | CYP3A5, CYP4F2, ACSL5 | KDM4E 372/4885MAPT 4054/4885ALDH1A1 284/4885 |
| US-20070254864-A1 | CHROMIUM COMPLEXES | PC, CS, PCCA | KDM4E 1944/4885MAPT 4505/4885ALDH1A1 1673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.