SCHEMBL8924822

SCHEMBL8924822

OCCCCOC1CCCOC1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.32
SPHK1 Q9NYA1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8926060 0.98 SPHK1 (0.34) ALDH1A1SPHK1
SCHEMBL9200574 0.95 PRMT5 (0.30) SPHK1
SCHEMBL28503324 0.90 MEN1 (0.35) SPHK1
SCHEMBL14763933 0.89 SPHK1 (0.39) ALDH1A1SPHK1
SCHEMBL9204047 0.87 PRMT5 (0.31)
SCHEMBL9036695 0.82
SCHEMBL8924819 0.82
SCHEMBL8926054 0.81 SPHK1 (0.31) SPHK1
SCHEMBL9036799 0.81 SPHK1 (0.31) SPHK1
SCHEMBL458567 0.81 ALDH1A1 (0.43) ALDH1A1SPHK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5639770-A SUPEROXIDE INHIBITOR OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1997-06-17 US disclosed
EP-0600092-A1 THIAZOLE DERIVATIVE OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-06-08 EP disclosed