Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MYOC | Q99972 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8925860 | 0.83 | ALDH1A1 (0.55) | ALDH1A1POLBKMT2AMAPTLMNA | |
| SCHEMBL429356 | 0.81 | ALDH1A1 (0.65) | ALDH1A1POLBCYP2C19RECQLMAPK1 | |
| SCHEMBL3528826 | 0.81 | ALDH1A1 (0.65) | ALDH1A1POLBCYP2C19RECQLMAPK1 | |
| SCHEMBL8926455 | 0.81 | POLB (0.65) | ALDH1A1POLBCYP2C19RECQLMAPK1 | |
| SCHEMBL10965695 | 0.80 | ALDH1A1 (0.63) | ALDH1A1POLBCYP2C19RECQLMAPK1 | |
| SCHEMBL8801283 | 0.80 | POLB (0.63) | ALDH1A1POLBCYP2C19RECQLMAPK1 | |
| SCHEMBL7717482 | 0.79 | POLB (0.61) | ALDH1A1POLBCYP2C19RECQLMAPK1 | |
| SCHEMBL13172617 | 0.78 | ALDH1A1 (0.60) | ALDH1A1POLBCYP2C19RECQLMAPK1 | |
| SCHEMBL22838071 | 0.78 | POLB (0.73) | ALDH1A1POLBCYP2C19RECQLMAPT | |
| SCHEMBL27890350 | 0.78 | ALDH1A1 (0.60) | ALDH1A1POLBCYP2C19RECQLMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663371-A | Process for preparing polycyclic dyes | ZENECA LIMITED (GB) | 1997-09-02 | — | — | US | disclosed |
| EP-0673400-A1 | POLYCYCLIC DYES | BASF AKTIENGESELLSCHAFT (DE) | 1995-09-27 | — | — | EP | disclosed |
| WO-1994012577-A2 | POLYCYCLIC DYES | ZENECA LIMITED (GB) | 1994-06-09 | — | — | WO | disclosed |