Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.73 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | BCL9 | O00512 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22838063 | 0.86 | ALDH1A1 (0.58) | POLBALDH1A1MAPTBCL9CTNNB1 | |
| SCHEMBL2385323 | 0.85 | POLB (0.61) | POLBALDH1A1RECQLCYP2C19HDAC3 | |
| SCHEMBL10965695 | 0.81 | ALDH1A1 (0.63) | POLBALDH1A1RECQLCYP2C19MAPT | |
| SCHEMBL429356 | 0.79 | ALDH1A1 (0.65) | POLBALDH1A1RECQLCYP2C19MAPT | |
| SCHEMBL3528826 | 0.79 | ALDH1A1 (0.65) | POLBALDH1A1RECQLCYP2C19MAPT | |
| SCHEMBL8926455 | 0.79 | POLB (0.65) | POLBALDH1A1RECQLCYP2C19MAPT | |
| SCHEMBL8801283 | 0.78 | POLB (0.63) | POLBALDH1A1RECQLCYP2C19MAPT | |
| SCHEMBL8924832 | 0.78 | ALDH1A1 (0.63) | POLBALDH1A1RECQLCYP2C19MAPT | |
| SCHEMBL22838091 | 0.77 | ALDH1A1 (0.43) | POLBALDH1A1CYP2C19HDAC1MAPT | |
| SCHEMBL7717482 | 0.76 | POLB (0.61) | POLBALDH1A1RECQLCYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11364220-B2 | Compounds and methods for inhibiting CPY26 enzymes | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2022-06-21 | — | — | US | disclosed |
| US-20210220326-A1 | Compounds and Methods for Inhibiting CPY26 Enzymes | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2021-07-22 | — | — | US | disclosed |
| US-10874634-B2 | Compounds and methods for inhibiting CYP26 enzymes | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2020-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10874634-B2 | Compounds and methods for inhibiting CYP26 enzymes | CYP26B1, CYP2A6, CYP26A1 | POLB 1323/4885ALDH1A1 110/4885RECQL 1338/4885 |
| US-11364220-B2 | Compounds and methods for inhibiting CPY26 enzymes | CYP2A6, CYP27A1, CYP26B1 | POLB 1876/4885ALDH1A1 700/4885RECQL 1461/4885 |
| US-20210220326-A1 | Compounds and Methods for Inhibiting CPY26 Enzymes | CYP2A6, CYP27A1, CYP26B1 | POLB 2078/4885ALDH1A1 772/4885RECQL 1698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.