Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.38 |
| ▸ | DGKA | P23743 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8924001 | 0.82 | ADRA2A (0.36) | DGKAADRB2KDM4EALDH1A1TDP1 | |
| SCHEMBL17036668 | 0.79 | DGKA (0.44) | EPHX2DGKAADRB2KDM4EALDH1A1 | |
| SCHEMBL12176701 | 0.79 | CYP1A2 (0.52) | ALDH1A1 | |
| SCHEMBL11190223 | 0.77 | DGKA (0.50) | EPHX2DGKAALDH1A1 | |
| SCHEMBL8923754 | 0.77 | DGKA (0.50) | EPHX2DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL104234 | 0.76 | TSHR (0.58) | EPHX2ALDH1A1 | |
| SCHEMBL667190 | 0.74 | DGKA (0.61) | EPHX2DGKAALDH1A1PRSS1PRSS2 | |
| SCHEMBL6973755 | 0.74 | DGKA (0.41) | DGKATDP1PRSS1PRSS2PRSS3 | |
| SCHEMBL6437701 | 0.73 | DGKA (0.70) | EPHX2DGKAKDM4EALDH1A1PRSS1 | |
| SCHEMBL7282921 | 0.73 | DGKA (0.59) | DGKAALDH1A1PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639770-A | SUPEROXIDE INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0600092-A1 | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |