Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22313796 | 0.96 | MEN1 (0.36) | MEN1KMT2ATSHRL3MBTL1CA12 | |
| SCHEMBL5463679 | 0.91 | TSHR (0.42) | MEN1KMT2ATSHRCA12CA9 | |
| SCHEMBL10171308 | 0.86 | TSHR (0.46) | MEN1KMT2ATSHRL3MBTL1CA12 | |
| SCHEMBL707591 | 0.86 | TSHR (0.46) | MEN1KMT2ATSHRL3MBTL1CA12 | |
| Acetic Acid SCHEMBL28209979 | 0.85 | GAA (0.39) | MEN1KMT2ATSHRCA12CA9 | |
| SCHEMBL21263699 | 0.83 | TDP1 (0.50) | MEN1KMT2ATSHRCA12CA9 | |
| SCHEMBL25983030 | 0.83 | CA12 (0.41) | MEN1KMT2ATSHRCA12CA9 | |
| SCHEMBL22313962 | 0.82 | DNM1 (0.40) | MEN1KMT2ATSHRCA12CA9 | |
| SCHEMBL21159200 | 0.82 | MEN1 (0.44) | MEN1KMT2ATSHRL3MBTL1CA12 | |
| SCHEMBL21652491 | 0.82 | TSHR (0.52) | MEN1KMT2ATSHRL3MBTL1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639770-A | SUPEROXIDE INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0600092-A1 | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |