Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | MGAM | O43451 | 2/20 | 0.42 |
| ▸ | SI | P14410 | 2/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL707591 | 0.95 | TSHR (0.46) | TSHRGAAMGAMSIMGAM2 | |
| SCHEMBL14201128 | 0.91 | TDP1 (0.42) | TSHRGAAMGAMSIMGAM2 | |
| Acetic Acid SCHEMBL28105432 | 0.88 | OPRK1 (0.45) | TSHRGAAMGAMSIMGAM2 | |
| SCHEMBL8924929 | 0.86 | MEN1 (0.39) | TSHRGAAMGAMSIMGAM2 | |
| SCHEMBL63502 | 0.86 | TSHR (0.53) | TSHRGAAMGAMSIMGAM2 | |
| SCHEMBL22313796 | 0.83 | MEN1 (0.36) | TSHRGAAMGAMSIMGAM2 | |
| SCHEMBL10283827 | 0.83 | L3MBTL1 (0.42) | TSHRGAAMGAMSIMGAM2 | |
| SCHEMBL10170339 | 0.83 | TSHR (0.36) | TSHRGAAMGAMSIMGAM2 | |
| SCHEMBL338996 | 0.81 | TSHR (0.48) | TSHRGAAMGAMSIMGAM2 | |
| SCHEMBL15549515 | 0.81 | TSHR (0.48) | TSHRGAAMGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160022842-A1 | FORMATION AND USES OF EUROPIUM | WAYNE STATE UNIVERSITY (US) | 2016-01-28 | — | — | US | disclosed |
| US-8895224-B2 | Lithographic printing plate precursors and processes for preparing lithographic printing plates | FUJIFILM CORPORATION (JP) | 2014-11-25 | — | — | US | disclosed |
| US-8449868-B2 | Preparation of cationic nanoparticles and personal care compositions comprising said nanoparticles | BASF SE (DE) | 2013-05-28 | — | — | US | disclosed |
| US-8101325-B2 | Azo compound, curable composition, color filter, and method of producing the same | FUJIFILM CORPORATION (JP) | 2012-01-24 | — | — | US | disclosed |
| WO-2010070126-A2 | SMART CONTRAST AGENTS FOR MRI IMAGING | UNIVERSITE DE ROUEN (FR) | 2010-06-24 | — | — | WO | disclosed |
| US-7507858-B2 | Histone deacetylase inhibitors | MERCK & CO., INC. (US) | 2009-03-24 | — | — | US | disclosed |
| US-20090075188-A1 | AZO COMPOUND, CURABLE COMPOSITION, COLOR FILTER, AND METHOD OF PRODUCING THE SAME | FUJIFILM CORPORATION (JP) | 2009-03-19 | — | — | US | disclosed |
| US-20080096920-A1 | Histone Deacetylase Inhibitors | MERCK SHARP & DOHME LLC | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096920-A1 | Histone Deacetylase Inhibitors | HDAC1, HDAC5, HDAC9 | TSHR 2354/4885GAA 333/4885MGAM 1462/4885 |
| US-20090075188-A1 | AZO COMPOUND, CURABLE COMPOSITION, COLOR FILTER, AND METHOD OF PRODUCING THE SAME | CRY1, RB1, CRY2 | TSHR 1408/4885GAA 4860/4885MGAM 4005/4885 |
| US-20160022842-A1 | FORMATION AND USES OF EUROPIUM | LETM1, CECR2, MCU | TSHR 1385/4885GAA 2515/4885MGAM 3167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.