SCHEMBL8924964

SCHEMBL8924964

CC1Cc2c(c(Cl)cc(Cl)c2-n2c(=O)cc(C(F)(F)F)n(C)c2=O)O1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.31
BRD4 O60885 1/20 0.30
CREBBP Q92793 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8924168 0.92 MAOA (0.30) MAOA
SCHEMBL7887203 0.81 MAOA (0.30) MAOA
SCHEMBL7889414 0.79 BRD4 (0.32) BRD4CREBBP
SCHEMBL9222964 0.78 NPSR1 (0.30)
SCHEMBL7891184 0.76 CREBBP (0.35) CREBBP
SCHEMBL9384318 0.72 MAOA (0.34) MAOA
SCHEMBL8391233 0.72
SCHEMBL9222926 0.72 PTGES (0.31)
SCHEMBL6794372 0.71
SCHEMBL8196825 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5602077-A CONTROLLING GROWTH OF UNDESIRED VEGETATION IN PLANTATION CROPS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1997-02-11 US claimed
WO-1993014073-A1 PYRIMIDIN COMPOUNDS USEFUL AS HERBICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-07-22 WO claimed
US-5602077-A CONTROLLING GROWTH OF UNDESIRED VEGETATION IN PLANTATION CROPS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1997-02-11 US disclosed
WO-1993014073-A1 PYRIMIDIN COMPOUNDS USEFUL AS HERBICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-07-22 WO disclosed