Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.45 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 3/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | EBP | Q15125 | 1/20 | 0.37 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8925043 | 0.85 | AR (0.39) | ACHEBCHEARKCNH2 | |
| SCHEMBL8925259 | 0.83 | AR (0.38) | SRD5A2ARKCNH2 | |
| SCHEMBL8926885 | 0.82 | SRD5A1 (0.43) | ACHESRD5A1SRD5A2ARKCNH2 | |
| SCHEMBL8724695 | 0.75 | SRD5A1 (0.42) | SRD5A1SRD5A2AR | |
| SCHEMBL8926415 | 0.74 | SRD5A1 (0.56) | SRD5A1SRD5A2 | |
| SCHEMBL8908656 | 0.72 | SRD5A1 (0.66) | SRD5A1SRD5A2 | |
| SCHEMBL8925516 | 0.71 | SRD5A1 (0.52) | SRD5A1SRD5A2 | |
| SCHEMBL8926945 | 0.71 | SRD5A1 (0.52) | SRD5A1SRD5A2 | |
| SCHEMBL8724838 | 0.69 | G6PD (0.40) | SRD5A2 | |
| SCHEMBL8909725 | 0.68 | AR (0.64) | SRD5A2ARKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693809-A | PREGNANES FOR TREATING ALOPECIA, ACNE AND SKIN DISORDER | MERCK & CO., INC. (US) | 1997-12-02 | — | — | US | disclosed |