Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8925043 | 0.89 | AR (0.39) | ARKCNH2KMT2A | |
| SCHEMBL8924975 | 0.83 | ACHE (0.45) | ARKCNH2SRD5A2 | |
| SCHEMBL8939839 | 0.73 | AR (0.33) | ARKCNH2KMT2A | |
| SCHEMBL8724838 | 0.73 | G6PD (0.40) | SRD5A2KMT2A | |
| SCHEMBL9663769 | 0.72 | SRD5A2 (0.42) | SRD5A2 | |
| SCHEMBL8926885 | 0.71 | SRD5A1 (0.43) | ARKCNH2SRD5A2KMT2A | |
| SCHEMBL9279736 | 0.70 | KMT2A (0.36) | SRD5A2KMT2A | |
| SCHEMBL8651043 | 0.68 | SRD5A1 (0.35) | SRD5A2KMT2A | |
| SCHEMBL8650483 | 0.68 | SRD5A1 (0.35) | SRD5A2KMT2A | |
| SCHEMBL8531759 | 0.68 | SRD5A1 (0.69) | SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693809-A | PREGNANES FOR TREATING ALOPECIA, ACNE AND SKIN DISORDER | MERCK & CO., INC. (US) | 1997-12-02 | — | — | US | disclosed |