SCHEMBL8924997

SCHEMBL8924997

CO/N=C(/C(=O)OC)c1ccccc1Oc1ccc(C)cc1

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 6/20 0.46
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
LMNA P02545 1/20 0.43
GAA P10253 1/20 0.42
HTT P42858 1/20 0.42
RAB9A P51151 2/20 0.42
PNLIP P16233 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
CTNNB1 P35222 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8925009 1.00 HIF1A (0.46) HIF1AMEN1KMT2ALMNAGAA
SCHEMBL8343946 0.90 HIF1A (0.53) HIF1AMEN1KMT2ALMNAGAA
SCHEMBL8761257 0.90 HIF1A (0.53) HIF1AMEN1KMT2ALMNAGAA
SCHEMBL9196461 0.90 HIF1A (0.53) HIF1AMEN1KMT2ALMNAGAA
SCHEMBL28826963 0.88 CTNNB1 (0.45) MEN1KMT2ALMNAGAAHTT
SCHEMBL8759366 0.88 LMNA (0.47) MEN1KMT2ALMNAGAAHTT
SCHEMBL8759357 0.88 LMNA (0.47) MEN1KMT2ALMNAGAAHTT
SCHEMBL8759311 0.87 MEN1 (0.42) MEN1KMT2ALMNAGAAHTT
SCHEMBL8368464 0.87 MEN1 (0.42) MEN1KMT2ALMNAGAAHTT
SCHEMBL8954683 0.86 HIF1A (0.52) HIF1AMEN1KMT2ALMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5650539-A ALKYLATION, ESTERIFICATION, DEESTERIFICATION, AMIDATION, FUNGICIDES SHIONOGI & CO., LTD. (JP) 1997-07-22 US disclosed
US-5488159-A AMIDATION, METHYLATION, FUNGICIDE SHIONOGI & CO., LTD. (JP) 1996-01-30 US disclosed
US-5380913-A E-Isomers of 2-methoxyimino-N-methyl-2-phenoxyphenylacetamides and alkyl 2-methoxyimino-2-phenoxyphenylacetates produced by reacting Z-isomers with hydrogen chloride or hydrochloric, sulfuric or toluenesulfonic acid in methyl, ethyl or butyl alc SHIONOGI & CO., LTD. (JP) 1995-01-10 US disclosed
EP-0468775-B1 Process for producing methoxyiminoacetamide compounds and intermediates SHIONOGI & CO (JP) 1994-12-14 EP disclosed
EP-0606924-A1 Process for producing E-isomers of methoxyminoacetamide compounds SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1994-07-20 EP disclosed
EP-0605392-A1 Process for producing methoxyminoacetamide compounds SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1994-07-06 EP disclosed
US-5183921-A Agricultural fungicides SHIONOGI & CO., LTD. (JP) 1993-02-02 US disclosed
EP-0468775-A1 Process for producing methoxyiminoacetamide compounds and intermediates SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1992-01-29 EP disclosed