Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922334 | 0.86 | CYP1A2 (0.51) | CYP1A2ALDH1A1POLBMAPK1MAPT | |
| SCHEMBL8923775 | 0.85 | CYP1A2 (0.50) | CYP1A2ALDH1A1POLBMAPK1MAPT | |
| SCHEMBL8924145 | 0.84 | CYP1A2 (0.49) | CYP1A2ALDH1A1POLBMAPK1MAPT | |
| SCHEMBL8924996 | 0.84 | CYP1A2 (0.49) | CYP1A2ALDH1A1POLBMAPK1MAPT | |
| SCHEMBL8924456 | 0.82 | CYP1A2 (0.47) | CYP1A2ALDH1A1POLBMAPK1MAPT | |
| SCHEMBL27740116 | 0.81 | CYP1A2 (0.51) | CYP1A2ALDH1A1POLBMAPK1MAPT | |
| SCHEMBL1301427 | 0.78 | CYP1A2 (0.77) | CYP1A2ALDH1A1POLBMAPK1MAPT | |
| SCHEMBL6202564 | 0.78 | CYP1A2 (0.53) | CYP1A2ALDH1A1POLBMAPK1MAPT | |
| SCHEMBL20524386 | 0.77 | ALDH1A1 (0.48) | CYP1A2ALDH1A1POLBMAPK1MAPT | |
| SCHEMBL20524434 | 0.76 | ALDH1A1 (0.47) | CYP1A2ALDH1A1POLBMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639770-A | SUPEROXIDE INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0600092-A1 | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |