Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 3/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6802602 | 0.86 | LTA4H (0.61) | TDP1ESR1ESR2LTA4HTSHR | |
| SCHEMBL12156440 | 0.80 | TDP1 (0.57) | TDP1ESR1ESR2LTA4HTSHR | |
| SCHEMBL8510027 | 0.77 | TDP1 (0.58) | TDP1ESR1ESR2LTA4HTSHR | |
| SCHEMBL6139276 | 0.77 | TDP1 (0.72) | TDP1TSHRRAB9ANPC1NFE2L2 | |
| SCHEMBL2022333 | 0.76 | KCNH2 (0.56) | TDP1LTA4HTSHRRAB9ANPC1 | |
| SCHEMBL56571 | 0.76 | KEAP1 (0.67) | TDP1LTA4HTSHRNFE2L2KEAP1 | |
| SCHEMBL555403 | 0.75 | TDP1 (0.65) | TDP1TSHRRAB9ANPC1NFE2L2 | |
| SCHEMBL12156578 | 0.75 | TDP1 (0.64) | TDP1LTA4HTSHRRAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL3570082 | 0.74 | KEAP1 (0.65) | TDP1LTA4HTSHRNFE2L2KEAP1 | |
| SCHEMBL12156398 | 0.74 | TDP1 (0.53) | TDP1LTA4HTSHRRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703266-A | OXIDATION HAIR DYES | L'OREAL (FR) | 1997-12-30 | — | — | US | disclosed |