Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTRN | P46939 | 4/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | CDC25A | P30304 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | CDC25C | P30307 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.32 |
| ▸ | CDK9 | P50750 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8925129 | 0.86 | UTRN (0.39) | UTRNNPY5RCDC25ACDC25BCDC25C | |
| SCHEMBL10331192 | 0.78 | CYP1A2 (0.52) | NPY5RCYP1A2CYP2A6CCNT1CDK9 | |
| SCHEMBL8992228 | 0.74 | ALDH1A1 (0.42) | UTRNNPY5RHDAC1 | |
| SCHEMBL8992208 | 0.73 | ALDH1A1 (0.53) | NPY5RHDAC1 | |
| SCHEMBL8992236 | 0.72 | TACR1 (0.42) | NPY5RHDAC1CYP1A2 | |
| SCHEMBL13267901 | 0.72 | HDAC1 (0.36) | NPY5RHDAC1CYP1A2CCNT1CDK9 | |
| SCHEMBL9166658 | 0.71 | NPY5R (0.42) | NPY5RHDAC1CYP1A2CYP2A6CCNT1 | |
| SCHEMBL13913134 | 0.69 | TSHR (0.50) | NPY5RCCNT1CDK9 | |
| SCHEMBL3109529 | 0.69 | NPY5R (0.49) | NPY5RHDAC1CCNT1CDK9 | |
| SCHEMBL13525456 | 0.69 | NPY5R (0.40) | NPY5RHDAC1CYP1A2CYP2A6CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5668121-A | Glutamate (NMDA) receptor antagonists | WARNER-LAMBERT COMPANY (US) | 1997-09-16 | — | — | US | disclosed |