Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 3/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8925526 | 0.86 | TACR1 (0.42) | TACR1MMP2MMP3NPY5R | |
| SCHEMBL6673661 | 0.80 | LMNA (0.37) | TACR1HDAC1LMNAGAANPY5R | |
| SCHEMBL8992210 | 0.79 | ALDH1A1 (0.43) | TACR1DHODHHDAC1KDM4EHTT | |
| SCHEMBL8992228 | 0.77 | ALDH1A1 (0.42) | HDAC1HSD17B1EPHX2NPY5R | |
| SCHEMBL8992208 | 0.75 | ALDH1A1 (0.53) | HDAC1KDM4EGAAHTTEPHX2 | |
| SCHEMBL6673664 | 0.74 | LMNA (0.39) | TACR1HDAC1LMNANPY5R | |
| SCHEMBL8925129 | 0.73 | UTRN (0.39) | GAAHTTSMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL8925123 | 0.72 | UTRN (0.39) | HDAC1CYP1A2NPY5R | |
| SCHEMBL8992214 | 0.72 | HDAC1 (0.33) | HDAC1HSD17B1EPHX2NPY5R | |
| SCHEMBL8823267 | 0.70 | ALDH1A1 (0.56) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489717-A | Glutamate (NMDA) receptor antagonists | WARNER-LAMBERT COMPANY | 1996-02-06 | — | — | US | disclosed |