SCHEMBL8925397

SCHEMBL8925397

C=CCCCCCCCCCc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 2/20 0.54
HDAC4 P56524 1/20 0.53
SIGMAR1 Q99720 9/20 0.52
USP2 O75604 1/20 0.52
ALDH1A1 P00352 1/20 0.52
HPGD P15428 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
MAOA P21397 1/20 0.50
MAPT P10636 1/20 0.48
RXFP1 Q9HBX9 1/20 0.48
MAOB P27338 2/20 0.48
TRPV1 Q8NER1 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL135515 1.00 HDAC1 (0.54) HDAC1HDAC4SIGMAR1USP2ALDH1A1
SCHEMBL1164061 1.00 HDAC1 (0.54) HDAC1HDAC4SIGMAR1USP2ALDH1A1
SCHEMBL136789 1.00 HDAC1 (0.54) HDAC1HDAC4SIGMAR1USP2ALDH1A1
SCHEMBL3689527 1.00 HDAC1 (0.54) HDAC1HDAC4SIGMAR1USP2ALDH1A1
SCHEMBL4635691 1.00 HDAC1 (0.54) HDAC1HDAC4SIGMAR1USP2ALDH1A1
SCHEMBL17183630 1.00 HDAC1 (0.54) HDAC1HDAC4SIGMAR1USP2ALDH1A1
SCHEMBL16550548 1.00 HDAC1 (0.54) HDAC1HDAC4SIGMAR1USP2ALDH1A1
SCHEMBL7625250 1.00 HDAC1 (0.54) HDAC1HDAC4SIGMAR1USP2ALDH1A1
SCHEMBL648362 0.98 MAOA (0.52) HDAC1HDAC4SIGMAR1USP2ALDH1A1
Nitrogen SCHEMBL10820909 0.96 HDAC1 (0.51) HDAC1HDAC4SIGMAR1USP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11492432-B2 Resin for nanoimprinting, laminate containing resin for nanoimprinting, printed board containing resin for nanoimprinting, and method for producing nanoimprint substrate JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2022-11-08 US disclosed
US-11078381-B2 Catechol-containing adhesive hydrogel, composition for preparing adhesive hydrogel, and compositions each including said adhesive hydrogel JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2021-08-03 US disclosed
US-11015010-B2 Block copolymer comprising catechol segment and inorganic nanoparticles coated by said block copolymer, as well as method for producing block copolymer comprising catechol segment and method for producing inorganic nanoparticles coated by said block copolymer JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2021-05-25 US disclosed
WO-2021080511-A1 METHODS OF BORYLATION AND USES THEREOF NATIONAL UNIVERSITY OF SINGAPORE (SG) 2021-04-29 WO disclosed
US-10851237-B2 Block copolymer, multilayered structure, solid polymer membrane, fuel cell, method for producing multilayered structure, and method for producing multilayered structure including inorganic nanoparticles JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2020-12-01 US disclosed
EP-3305866-B1 CATECHOL-CONTAINING ADHESIVE HYDROGEL, COMPOSITION FOR PREPARING ADHESIVE HYDROGEL, AND COMPOSITIONS EACH INCLUDING SAID ADHESIVE HYDROGEL JAPAN SCIENCE & TECH AGENCY (JP) 2020-07-29 EP disclosed
US-20200223125-A1 RESIN FOR NANOIMPRINTING, LAMINATE CONTAINING RESIN FOR NANOIMPRINTING, PRINTED BOARD CONTAINING RESIN FOR NANOIMPRINTING, AND METHOD FOR PRODUCING NANOIMPRINT SUBSTRATE JAPAN SCIENCE & TECH AGENCY (JP) 2020-07-16 US disclosed
US-20200190362-A1 CATECHOL-CONTAINING ADHESIVE HYDROGEL, COMPOSITION FOR PREPARING ADHESIVE HYDROGEL, AND COMPOSITIONS EACH INCLUDING SAID ADHESIVE HYDROGEL JAPAN SCIENCE & TECH AGENCY (JP) 2020-06-18 US disclosed
US-10611927-B2 Catechol-containing adhesive hydrogel, composition for preparing adhesive hydrogel, and compositions each including said adhesive hydrogel JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2020-04-07 US disclosed
US-20190169420-A1 BLOCK COPOLYMER, MULTILAYER STRUCTURE, SOLID POLYMER FILM, FUEL CELL, PRODUCTION METHOD FOR MULTILAYER STRUCTURE, AND PRODUCTION METHOD FOR MULTILAYER STRUCTURE CONTAINING INORGANIC NANOPARTICLES JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2019-06-06 US disclosed
EP-3112387-A1 BLOCK COPOLYMER CONTAINING CATECHOL SEGMENT, INORGANIC NANOPARTICLES COATED BY SAID BLOCK COPOLYMER, METHOD FOR PRODUCING BLOCK COPOLYMER CONTAINING CATECHOL SEGMENT, AND METHOD FOR PRODUCING INORGANIC NANOPARTICLES COATED BY SAID BLOCK COPOLYMER Japan Science and Technology Agency (JP) 2017-01-04 EP disclosed
US-20150298387-A1 RESIN FOR NANOIMPRINTING, LAMINATE CONTAINING RESIN FOR NANOIMPRINTING, PRINTED BOARD CONTAINING RESIN FOR NANOIMPRINTING, AND METHOD FOR PRODUCING NANOIMPRINT SUBSTRATE JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2015-10-22 US disclosed
US-9040596-B2 Organo-copper reagents for attaching perfluorosulfonic acid groups to polyolefins GM Global Technology Operations LLC (US) 2015-05-26 US disclosed
CN-103360523-A Partly fluorinated polyolefins by Ziegler-Natta polymerization GM GLOBAL TECH OPERATIONS INC 2013-10-23 CN disclosed
US-20130171528-A1 Organo-Copper Reagents for Attaching Perfluorosulfonic Acid Groups to Polyolefins GM Global Technology Operations LLC (US) 2013-07-04 US disclosed
US-5646098-A Carbonyl containing compounds and their derivatives as multi-functional fuel and lube additives EXXON CHEMICAL PATENTS INC (US) 1997-07-08 US disclosed
US-5550241-A Adducts of cyclic carbonyl monomers and substituted alkens EXXON RESEARCH AND ENGINEERING COMPANY (US) 1996-08-27 US disclosed
US-5145844-A Enzyme inhibitors, antiinflammatory agents, analgesics HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1992-09-08 US disclosed
US-5030733-A Analgesics, antiinflammatory agents, phospholipase inhibitor HOECHST-ROUSSEL PHARMACETICALS INCORPORATED (US) 1991-07-09 US disclosed
EP-0300397-A2 Hydroxy-, Alkoxy- and Benzyloxy substituted phospholipids, a process for their preparation and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1989-01-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200190362-A1 CATECHOL-CONTAINING ADHESIVE HYDROGEL, COMPOSITION FOR PREPARING ADHESIVE HYDROGEL, AND COMPOSITIONS EACH INCLUDING SAID ADHESIVE HYDROGEL CDH1, CD44, COMT HDAC1 3554/4885HDAC4 3881/4885SIGMAR1 2844/4885
US-11078381-B2 Catechol-containing adhesive hydrogel, composition for preparing adhesive hydrogel, and compositions each including said adhesive hydrogel CDH1, CD44, COMT HDAC1 3554/4885HDAC4 3881/4885SIGMAR1 2844/4885
US-10611927-B2 Catechol-containing adhesive hydrogel, composition for preparing adhesive hydrogel, and compositions each including said adhesive hydrogel CDH1, CD44, COMT HDAC1 3554/4885HDAC4 3881/4885SIGMAR1 2844/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.