Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18390275 | 0.74 | GAA (0.60) | GAAKDM4EGLAIGF1RALDH1A1 | |
| SCHEMBL8923742 | 0.71 | CYP2D6 (0.32) | KDM4E | |
| SCHEMBL352281 | 0.70 | GAA (1.00) | GAAKDM4EIGF1RALDH1A1MEN1 | |
| SCHEMBL18390276 | 0.70 | GAA (0.68) | GAAKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL8924736 | 0.69 | TSHR (0.39) | KDM4EALDH1A1LMNAHTR1A | |
| SCHEMBL4071515 | 0.67 | — | — | |
| SCHEMBL4070702 | 0.67 | — | — | |
| SCHEMBL4072954 | 0.67 | — | — | |
| SCHEMBL31341343 | 0.67 | GAA (0.90) | GAAKDM4EIGF1RALDH1A1MEN1 | |
| SCHEMBL2066587 | 0.65 | HTR3A (0.42) | GAAGLAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639770-A | SUPEROXIDE INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0600092-A1 | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |