Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 5/20 | 0.39 |
| ▸ | PPARA | Q07869 | 5/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8992322 | 0.91 | ALDH1A1 (0.51) | ALDH1A1RECQLNPY5RPPARGPPARA | |
| SCHEMBL8992228 | 0.85 | ALDH1A1 (0.42) | ALDH1A1RECQLNPY5RPPARGMMP8 | |
| SCHEMBL8992329 | 0.83 | ALDH1A1 (0.41) | ALDH1A1RECQLNPY5RPPARGPPARA | |
| SCHEMBL8992331 | 0.82 | PPARG (0.39) | ALDH1A1NPY5RPPARGPPARACYP2C9 | |
| SCHEMBL9704697 | 0.82 | ALDH1A1 (0.50) | ALDH1A1RECQLNPY5RMMP8MAPT | |
| SCHEMBL8925526 | 0.78 | TACR1 (0.42) | ALDH1A1NPY5RPPARGPPARAHPGD | |
| SCHEMBL6051883 | 0.77 | ALDH1A1 (0.51) | ALDH1A1RECQLNPY5RMMP8KDM4E | |
| SCHEMBL8992208 | 0.76 | ALDH1A1 (0.53) | ALDH1A1RECQLNPY5RKDM4EL3MBTL1 | |
| SCHEMBL4413223 | 0.71 | KDM4E (0.45) | ALDH1A1NPY5RHPGDKDM4ELMNA | |
| SCHEMBL8992210 | 0.69 | ALDH1A1 (0.43) | ALDH1A1RECQLNPY5RKDM4ETHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5668121-A | Glutamate (NMDA) receptor antagonists | WARNER-LAMBERT COMPANY (US) | 1997-09-16 | — | — | US | disclosed |
| US-5489717-A | Glutamate (NMDA) receptor antagonists | WARNER-LAMBERT COMPANY | 1996-02-06 | — | — | US | disclosed |