Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | DHODH | Q02127 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8992208 | 0.90 | ALDH1A1 (0.53) | ALDH1A1RECQLATMEPHX2PKM | |
| SCHEMBL8992329 | 0.86 | ALDH1A1 (0.41) | ALDH1A1RECQLATMTACR1PKM | |
| SCHEMBL8992228 | 0.83 | ALDH1A1 (0.42) | ALDH1A1RECQLATMEPHX2HDAC1 | |
| SCHEMBL8992236 | 0.79 | TACR1 (0.42) | TACR1EPHX2KDM4EDHODHHTT | |
| SCHEMBL8992214 | 0.76 | HDAC1 (0.33) | ALDH1A1RECQLEPHX2HDAC1NPY5R | |
| SCHEMBL8992322 | 0.76 | ALDH1A1 (0.51) | ALDH1A1RECQLATMPKMKDM4E | |
| SCHEMBL8925129 | 0.74 | UTRN (0.39) | ALDH1A1HTTNPY5RSLC6A2SLC6A4 | |
| SCHEMBL8925123 | 0.71 | UTRN (0.39) | HDAC1NPY5R | |
| SCHEMBL10771167 | 0.69 | ALDH1A1 (0.60) | ALDH1A1RECQLATMPKMKDM4E | |
| SCHEMBL10771109 | 0.69 | ATM (0.56) | ALDH1A1RECQLATMPKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489717-A | Glutamate (NMDA) receptor antagonists | WARNER-LAMBERT COMPANY | 1996-02-06 | — | — | US | claimed |