Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 10/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8924318 | 0.81 | PTGS2 (0.63) | NR3C2PTGS2PTGS1 | |
| SCHEMBL3867900 | 0.78 | PTGS2 (0.47) | PTGS2KCNH2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3980093 | 0.78 | PTGS2 (0.44) | PTGS2KCNH2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1595377 | 0.76 | NR3C2 (0.53) | NR3C2PTGS2KCNH2SMN1; SMN2GCGR | |
| SCHEMBL29496568 | 0.76 | NR1H2 (0.57) | NR3C2PTGS2PTGS1KCNH2 | |
| SCHEMBL16566078 | 0.76 | NR1H2 (0.57) | NR3C2PTGS2PTGS1KCNH2 | |
| SCHEMBL6722182 | 0.75 | NR3C2 (0.49) | NR3C2PTGS2PTGS1KCNH2 | |
| SCHEMBL13193333 | 0.75 | PTGS2 (0.48) | NR3C2PTGS2PTGS1KCNH2 | |
| SCHEMBL3863759 | 0.74 | FAAH (0.40) | PTGS2ALDH1A1HPGDGCGR | |
| SCHEMBL3869299 | 0.74 | FAAH (0.40) | PTGS2ALDH1A1HPGDGCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670533-A | ANTIINFLAMMATORY AGENTS, ANALGESICS OR ANTIRHEUMATIC DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |
| US-5550147-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTITHROMBOTIC AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| EP-0554829-A2 | Pyrazole derivatives with antiinflammatory, analgesic and antithrombolic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-11 | — | — | EP | disclosed |