Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 5/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
| ▸ | RELA | Q04206 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | RPA1 | P27694 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 12/20 | 0.49 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8641975 | 0.88 | RPA1 (0.67) | MEN1KMT2ARPA1KDM1A | |
| SCHEMBL3870127 | 0.87 | RPA1 (0.52) | RPA1KDM1A | |
| SCHEMBL8925672 | 0.84 | MALT1 (0.60) | MALT1NFKB1NFKB2RELAMEN1 | |
| SCHEMBL8922991 | 0.82 | CA9 (0.56) | RPA1KDM1A | |
| SCHEMBL7462301 | 0.75 | PTGS2 (0.65) | RPA1 | |
| SCHEMBL7461307 | 0.75 | PTGS2 (0.67) | — | |
| SCHEMBL20837670 | 0.75 | KDM1A (0.63) | RPA1KDM1ASMPD1 | |
| SCHEMBL22892054 | 0.75 | SMN1; SMN2 (0.71) | MEN1KMT2ARPA1KDM1ASMPD1 | |
| SCHEMBL16797389 | 0.75 | SMN1; SMN2 (0.71) | MEN1KMT2ARPA1KDM1ASMPD1 | |
| SCHEMBL16797379 | 0.74 | KDM1A (0.60) | RPA1KDM1ASMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670533-A | ANTIINFLAMMATORY AGENTS, ANALGESICS OR ANTIRHEUMATIC DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |
| US-5550147-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTITHROMBOTIC AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| EP-0554829-A2 | Pyrazole derivatives with antiinflammatory, analgesic and antithrombolic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-11 | — | — | EP | disclosed |