Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 5/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.60 |
| ▸ | RELA | Q04206 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | RPA1 | P27694 | 1/20 | 0.51 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 7/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9201687 | 0.86 | MALT1 (0.63) | MALT1NFKB1NFKB2RELAMEN1 | |
| SCHEMBL9209545 | 0.86 | AOC3 (0.66) | MALT1NFKB1NFKB2RELAMEN1 | |
| SCHEMBL8925772 | 0.84 | MALT1 (0.61) | MALT1NFKB1NFKB2RELAMEN1 | |
| SCHEMBL3865450 | 0.82 | PTGS2 (0.58) | CA9CA1CA2PTGS2HDAC3 | |
| SCHEMBL8421963 | 0.81 | PTGS2 (0.64) | CA9CA1CA2PTGS2 | |
| SCHEMBL7459996 | 0.81 | PTGS2 (0.62) | CA9CA1CA2PTGS2 | |
| SCHEMBL9202590 | 0.81 | MALT1 (0.56) | MALT1NFKB1NFKB2RELAMEN1 | |
| SCHEMBL9202586 | 0.81 | MALT1 (0.56) | MALT1NFKB1NFKB2RELAMEN1 | |
| SCHEMBL7466476 | 0.78 | PTGS2 (0.74) | CA9CA1CA2PTGS2HDAC3 | |
| SCHEMBL3865581 | 0.77 | PTGS2 (0.78) | CA9CA1CA2PTGS2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670533-A | ANTIINFLAMMATORY AGENTS, ANALGESICS OR ANTIRHEUMATIC DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |
| US-5550147-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTITHROMBOTIC AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| EP-0554829-A2 | Pyrazole derivatives with antiinflammatory, analgesic and antithrombolic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-11 | — | — | EP | disclosed |