Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11203828 | 0.82 | MAPT (0.50) | MAPTRXFP1MAPK1HDAC1ALOX5 | |
| SCHEMBL11268263 | 0.82 | LMNA (0.58) | MAPTABCB11LMNAMAPK1 | |
| SCHEMBL11268538 | 0.82 | LMNA (0.58) | MAPTABCB11LMNAMAPK1 | |
| SCHEMBL11266263 | 0.82 | LMNA (0.58) | MAPTABCB11LMNAMAPK1 | |
| SCHEMBL11275748 | 0.82 | LMNA (0.58) | MAPTABCB11LMNAMAPK1 | |
| SCHEMBL11270686 | 0.80 | MAPT (0.49) | MAPTRXFP1MAPK1HDAC1ALOX5 | |
| SCHEMBL11269898 | 0.80 | LMNA (0.56) | MAPTABCB11LMNAMAPK1 | |
| SCHEMBL11205171 | 0.78 | HDAC1 (0.49) | MAPTRXFP1MAPK1HDAC1ALOX5 | |
| SCHEMBL11209645 | 0.78 | MAPT (0.46) | MAPTRXFP1MAPK1HDAC1ALOX5 | |
| SCHEMBL11271674 | 0.78 | POLB (0.43) | MAPTLMNAMAPK1HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693857-A | Process and intermediate for the preparation of 2-hydroxy-3-sulfido-3-phenyl propanoic acids | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |