Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11203828 | 0.98 | MAPT (0.50) | MAPTRXFP1FDFT1HDAC1HDAC2 | |
| SCHEMBL11209541 | 0.92 | HDAC3 (0.47) | MAPTRXFP1FDFT1HDAC1HDAC2 | |
| SCHEMBL11209645 | 0.85 | MAPT (0.46) | MAPTRXFP1FDFT1HDAC1HDAC2 | |
| SCHEMBL11205171 | 0.85 | HDAC1 (0.49) | MAPTRXFP1HDAC1HDAC2ALOX5 | |
| Clomoxir SCHEMBL112980 | 0.85 | ABCB11 (0.47) | MAPTHDAC1HDAC2HDAC3MAPK1 | |
| SCHEMBL11275748 | 0.80 | LMNA (0.58) | MAPTMAPK1 | |
| SCHEMBL11268263 | 0.80 | LMNA (0.58) | MAPTMAPK1 | |
| SCHEMBL8925815 | 0.80 | MAPT (0.42) | MAPTRXFP1HDAC1HDAC2ALOX5 | |
| SCHEMBL11266263 | 0.80 | LMNA (0.58) | MAPTMAPK1 | |
| SCHEMBL11268538 | 0.80 | LMNA (0.58) | MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4324796-A | HYPOGLYCEMIC AGENTS, HYPOKETONEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-04-13 | — | — | US | disclosed |