Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8925641 | 0.87 | NR1I2 (0.64) | NR1I2CYP3A4CYP2D6HDAC6 | |
| SCHEMBL8921466 | 0.81 | NR1I2 (0.45) | NR1I2CYP3A4CYP2D6L3MBTL1TDP1 | |
| SCHEMBL8924593 | 0.80 | CYP3A4 (0.44) | NR1I2CYP3A4CYP2D6HDAC6L3MBTL1 | |
| SCHEMBL9200266 | 0.76 | NR1I2 (0.73) | NR1I2CYP3A4CYP2D6L3MBTL1TDP1 | |
| SCHEMBL8824399 | 0.76 | NR1I2 (0.52) | NR1I2CYP3A4CYP2D6L3MBTL1TDP1 | |
| SCHEMBL9087864 | 0.74 | NR1I2 (0.47) | NR1I2CYP3A4CYP2D6L3MBTL1TDP1 | |
| SCHEMBL8824422 | 0.74 | NR1I2 (0.53) | NR1I2CYP3A4CYP2D6L3MBTL1TDP1 | |
| SCHEMBL8670645 | 0.74 | CYP3A4 (0.48) | NR1I2CYP3A4CYP2D6L3MBTL1TDP1 | |
| SCHEMBL8553518 | 0.74 | NR1I2 (0.49) | NR1I2CYP3A4CYP2D6L3MBTL1TDP1 | |
| SCHEMBL8824435 | 0.73 | NR1I2 (0.49) | NR1I2CYP3A4CYP2D6HDAC6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618821-A | VIRICIDES, PICORNAVIRUS | SANOFI, S.A. (FR) | 1997-04-08 | — | — | US | disclosed |
| WO-1995031438-A1 | THERAPEUTIC PHENOXYALKYLHETEROCYCLES | SANOFI WINTHROP, INC. (US) | 1995-11-23 | — | — | WO | disclosed |