Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 0.53 |
| ▸ | CTSS | P25774 | 3/20 | 0.53 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8925924 | 1.00 | CTSK (0.53) | CTSKCTSSNOD1PPARGPPARA | |
| SCHEMBL22371758 | 0.91 | CTSK (0.51) | CTSKCTSSPPARGPPARACAPN1 | |
| SCHEMBL22371757 | 0.91 | CTSK (0.51) | CTSKCTSSPPARGPPARACAPN1 | |
| SCHEMBL27611196 | 0.87 | CTSK (0.49) | CTSKCTSSPPARGPPARACAPN1 | |
| SCHEMBL3604134 | 0.87 | CTSK (0.49) | CTSKCTSSPPARGPPARACAPN1 | |
| SCHEMBL345582 | 0.86 | CTSK (0.68) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL3448997 | 0.86 | CTSK (0.68) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL1350139 | 0.86 | CTSK (0.68) | CTSKCTSSMEN1GAAKMT2A | |
| Hydrochloric Acid SCHEMBL6037571 | 0.85 | CTSK (0.66) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL3233192 | 0.85 | CTSK (0.62) | CTSKCTSSNOD1MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624939-A | N-acyl pyrrolidines and drugs for the treatment or prevention of cholecystokinin and gastrin-related disorders | RHONE-POULENC RORER, S.A. (FR) | 1997-04-29 | — | — | US | disclosed |