SCHEMBL3448997

SCHEMBL3448997

CCCC[C@@H](NC(=O)OC(C)(C)C)C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CTSK P43235 18/20 0.68
CTSS P25774 3/20 0.68
MEN1 O00255 1/20 0.49
GAA P10253 1/20 0.49
KMT2A Q03164 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1350139 1.00 CTSK (0.68) CTSKCTSSMEN1GAAKMT2A
SCHEMBL345582 1.00 CTSK (0.68) CTSKCTSSMEN1GAAKMT2A
Hydrochloric Acid SCHEMBL6037571 0.98 CTSK (0.66) CTSKCTSSMEN1GAAKMT2A
SCHEMBL14820490 0.95 CTSK (0.62) CTSKCTSSMEN1GAAKMT2A
SCHEMBL18875931 0.95 CTSK (0.62) CTSKCTSSMEN1GAAKMT2A
SCHEMBL3233192 0.95 CTSK (0.62) CTSKCTSSMEN1GAAKMT2A
SCHEMBL29826317 0.94 CTSK (0.69) CTSKCTSS
SCHEMBL7555645 0.94 CTSK (0.60) CTSKCTSS
SCHEMBL5050858 0.94 CTSK (0.60) CTSKCTSS
SCHEMBL7555646 0.94 CTSK (0.60) CTSKCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118955391-A Substituted N- (2-oxo ethyl) benzamide derivative and preparation method and application thereof 中国医学科学院医药生物技术研究所 2024-11-15 CN disclosed
WO-2024163962-A1 3-((1,1-DIOXIDO-2,3,4,5-TETRAHYDROBENZO[F][1,2,5]THIADIAZEPIN-8-YL)OXY)-2-FLUOROACRYLIC ACID DERIVATIVES AS SODIUM TAUROCHOLATE CO-TRANSPORTING POLYPEPTIDE (NTCP) INHIBITORS FOR THE TREATMENT OF CHOLESTASIS Hemoshear Therapeutics, Inc. (US) 2024-08-08 WO disclosed
US-20240226343-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. 2024-07-11 US disclosed
US-11932628-B2 Selective small molecule peptidomimetic melanocortin ligands REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2024-03-19 US disclosed
US-20230398226-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS CIDARA THERAPEUTICS, INC. 2023-12-14 US disclosed
US-11833213-B2 Compositions and methods for the treatment of viral infections CIDARA THERAPEUTICS, INC. (US) 2023-12-05 US disclosed
US-20220213068-A1 SELECTIVE SMALL MOLECULE PEPTIDOMIMETIC MELANOCORTIN LIGANDS TORREY PINES INSTITUTE FOR MOLECULAR STUDIES 2022-07-07 US disclosed
US-20220177471-A1 N-1 BRANCHED ALKYL SUBSTITUTED IMIDAZO[4,5-C]QUINOLINE COMPOUNDS, COMPOSITIONS, AND METHODS SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2022-06-09 US disclosed
EP-3980415-A1 N-1 BRANCHED ALKYL SUBSTITUTED IMIDAZO[4,5-C]QUINOLINE COMPOUNDS, COMPOSITIONS, AND METHODS 3M Innovative Properties Company (US) 2022-04-13 EP disclosed
CN-113924297-A N-1 branched alkyl substituted imidazo [4,5-c ] quinoline compounds, compositions, and methods 3M创新有限公司 2022-01-11 CN disclosed
EP-1695961-A1 UREA DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE Takeda Pharmaceutical Company Limited (JP) 2006-08-30 EP disclosed
US-6242494-B1 ANGIOGENESIS INHIBITORS, ANTITUMOR AGENTS, DIABETIC RETINOPATHY, AND ANTIINFLAMMATORY AGENTS ABBOTT LABORATORIES 2001-06-05 US disclosed
EP-1073633-A2 SUBSTITUTED BETA-AMINO ACID INHIBITORS OF METHIONINE AMINOPEPTIDASE-2 ABBOTT LABORATORIES (US) 2001-02-07 EP disclosed
WO-1999057098-A2 SUBSTITUTED BETA-AMINO ACID INHIBITORS OF METHIONINE AMINOPEPTIDASE-2 ABBOTT LABORATORIES (US) 1999-11-11 WO disclosed
EP-0136720-B1 ENKEPHALIN ANALOGS G.D. Searle & Co. (US) 1989-09-20 EP disclosed
US-4603121-A ANALGESICS G. D. SEARLE & CO. (US) 1986-07-29 US disclosed
EP-0136720-A2 Enkephalin analogs G.D. Searle & Co. (US) 1985-04-10 EP disclosed
EP-0033504-B1 PENTAPEPTIDES OF THE ENCEPHALINE TYPE, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE Richter Gedeon Vegyészeti Gyár R.T. (HU) 1984-10-24 EP disclosed
US-4339440-A HYPOTENSIVES RICHTER GEDEON VEGYESZETI GYAR RT (HU) 1982-07-13 US disclosed
EP-0033504-A2 Pentapeptides of the encephaline type, process for their preparation and medicaments containing these Richter Gedeon Vegyészeti Gyár R.T. (HU) 1981-08-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230398226-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS FCGR3B, ALB, FCGR1A CTSK 315/4885CTSS 116/4885MEN1 3968/4885
US-11932628-B2 Selective small molecule peptidomimetic melanocortin ligands MC1R, MC3R, MC4R CTSK 2752/4885CTSS 3135/4885MEN1 137/4885
US-11833213-B2 Compositions and methods for the treatment of viral infections FCGR3B, ALB, FCGR1A CTSK 315/4885CTSS 116/4885MEN1 3968/4885
US-20220213068-A1 SELECTIVE SMALL MOLECULE PEPTIDOMIMETIC MELANOCORTIN LIGANDS MC1R, MC3R, MC4R CTSK 2752/4885CTSS 3135/4885MEN1 137/4885
US-20220177471-A1 N-1 BRANCHED ALKYL SUBSTITUTED IMIDAZO[4,5-C]QUINOLINE COMPOUNDS, COMPOSITIONS, AND METHODS IFNG, IFNAR1, IRF3 CTSK 3049/4885CTSS 2581/4885MEN1 1110/4885
US-20240226343-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF NPY1R, NPY2R, NPY4R CTSK 798/4885CTSS 1279/4885MEN1 601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.