SCHEMBL8926253

SCHEMBL8926253

C=CC/C=C(/C(N)=O)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.35
LDHB P07195 1/20 0.35
HTT P42858 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
FGFR4 P22455 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10604078 1.00 LDHA (0.35) LDHALDHBHTTALDH1A1TSHR
SCHEMBL1135898 0.85 EP300 (0.38) ALDH1A1TSHR
SCHEMBL28537317 0.76
SCHEMBL6685557 0.76
SCHEMBL45771 0.76
SCHEMBL29423 0.76
SCHEMBL170794 0.73
Urea SCHEMBL27790776 0.73 ALDH1A1 (0.36) HTTALDH1A1TSHRFGFR4
SCHEMBL1135184 0.71 GRIK1 (0.41) LDHALDHB
SCHEMBL27985112 0.71 GRIK1 (0.41) LDHALDHB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5698270-A Process for the preparation of antiscratch and antiabrasion shaped articles based on acrylic polymers ATOHAAS HOLDING C.V. 1997-12-16 US claimed
US-5698270-A Process for the preparation of antiscratch and antiabrasion shaped articles based on acrylic polymers ATOHAAS HOLDING C.V. 1997-12-16 US disclosed