Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSD | A5PKW4 | 1/20 | 0.47 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.44 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 11/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GYS1 | P13807 | 1/20 | 0.42 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | ILK | Q13418 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5078441 | 0.85 | PTGS2 (0.53) | PTGS2ALDH1A1 | |
| SCHEMBL8766048 | 0.85 | PTGS2 (0.53) | PTGS2 | |
| SCHEMBL6180483 | 0.85 | PTGS2 (0.53) | PTGS2ALDH1A1 | |
| SCHEMBL8925681 | 0.84 | GSK3B (0.44) | PSDABCC8KCNJ11PTGS2ALDH1A1 | |
| SCHEMBL8926251 | 0.84 | MEN1 (0.49) | PSDABCC8KCNJ11PTGS2ALDH1A1 | |
| SCHEMBL4212020 | 0.84 | PTGS2 (0.52) | PTGS2ALDH1A1 | |
| SCHEMBL8925320 | 0.81 | PTGS2 (0.47) | PTGS2 | |
| SCHEMBL8640384 | 0.79 | PTGS2 (0.45) | PTGS2CA12CA1CA2CA9 | |
| SCHEMBL8925255 | 0.77 | PTGS2 (0.41) | PTGS2 | |
| SCHEMBL8764854 | 0.77 | PTGS2 (0.53) | PTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670533-A | ANTIINFLAMMATORY AGENTS, ANALGESICS OR ANTIRHEUMATIC DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |