Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 16/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8925320 | 0.91 | PTGS2 (0.47) | PTGS2PTGS1PTGDR2 | |
| SCHEMBL8642544 | 0.83 | — | — | |
| SCHEMBL6180483 | 0.83 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL8766048 | 0.83 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL5078441 | 0.83 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL8637993 | 0.82 | RXFP1 (0.34) | PTGS2CA12CA1CA2CA4 | |
| SCHEMBL4212020 | 0.82 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL8926255 | 0.79 | PSD (0.47) | PTGS2CA12CA1CA2CA9 | |
| SCHEMBL8925536 | 0.78 | PTGS2 (0.44) | PTGS2PTGDR2 | |
| SCHEMBL8925255 | 0.77 | PTGS2 (0.41) | PTGS2PTGS1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0856000-A1 | 1,3,5-TRISUBSTITUTED PYRAZOLES FOR TREAMENT OF INFLAMMATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-08-05 | — | — | EP | disclosed |
| WO-1997013755-A1 | 1,3,5-TRISUBSTITUTED PYRAZOLES FOR TREAMENT OF INFLAMMATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-17 | — | — | WO | disclosed |