SCHEMBL8926261

SCHEMBL8926261

C=C(CC=CC(N)=O)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.35
GRIK1 P39086 1/20 0.35
GRIK2 Q13002 1/20 0.35
GRM1 Q13255 1/20 0.35
GRM2 Q14416 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TET2 Q6N021 4/20 0.32
TET3 O43151 1/20 0.32
TET1 Q8NFU7 1/20 0.32
TSHR P16473 2/20 0.32
ALDH1A1 P00352 2/20 0.32
FGFR4 P22455 1/20 0.32
GABRR1 P24046 2/20 0.31
GABRR2 P28476 2/20 0.31
BLM P54132 2/20 0.31
GABRR3 A8MPY1 1/20 0.31
LMNA P02545 1/20 0.31
APEX1 P27695 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9853791 0.81 TSHR (0.44) ALOX15GRIK1GRIK2GRM1GRM2
SCHEMBL306251 0.81 TSHR (0.44) ALOX15GRIK1GRIK2GRM1GRM2
SCHEMBL11126445 0.80 ALOX15 (0.47) ALOX15GRIK1GRIK2GRM1GRM2
SCHEMBL11241202 0.80 ALOX15 (0.47) ALOX15GRIK1GRIK2GRM1GRM2
SCHEMBL16111614 0.77 ALOX15 (0.35) ALOX15GRIK1GRIK2GRM1GRM2
SCHEMBL45774 0.76
SCHEMBL17824377 0.75
SCHEMBL989707 0.75 ALDH1A1 (0.37) ALDH1A1
Methacrylic Acid SCHEMBL3632983 0.74 TSHR (0.38) ALOX15HSD17B10TET2TET3TET1
SCHEMBL87513 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5698270-A Process for the preparation of antiscratch and antiabrasion shaped articles based on acrylic polymers ATOHAAS HOLDING C.V. 1997-12-16 US claimed
US-5698270-A Process for the preparation of antiscratch and antiabrasion shaped articles based on acrylic polymers ATOHAAS HOLDING C.V. 1997-12-16 US disclosed
US-4336318-A ADJUSTING THE THICKNESS OF TONE LAYER TO PRODUCE FOG FREE IMAGES CANON KABUSHIKI KAISHA (JP) 1982-06-22 US disclosed