Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | VDR | P11473 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8925157 | 0.88 | SRD5A2 (0.32) | ARKCNH2G6PDSRD5A2CYP2C9 | |
| SCHEMBL8926809 | 0.85 | SRD5A1 (0.37) | ARKCNH2SRD5A2 | |
| SCHEMBL8925443 | 0.82 | AR (0.34) | ARKCNH2SRD5A2 | |
| SCHEMBL8927169 | 0.82 | G6PD (0.36) | ARKCNH2G6PDSRD5A2 | |
| SCHEMBL8927275 | 0.78 | AR (0.37) | ARKCNH2SRD5A2GPBAR1 | |
| SCHEMBL8927033 | 0.77 | AR (0.36) | ARKCNH2G6PDSRD5A2GPBAR1 | |
| SCHEMBL8925996 | 0.77 | ALDH1A1 (0.37) | KCNH2SRD5A2CYP2C9HRH3 | |
| SCHEMBL8926427 | 0.77 | SRD5A1 (0.52) | SRD5A2 | |
| SCHEMBL8927056 | 0.76 | SRD5A2 (0.33) | ARKCNH2SRD5A2 | |
| SCHEMBL8926814 | 0.76 | SRD5A2 (0.33) | ARKCNH2SRD5A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693809-A | PREGNANES FOR TREATING ALOPECIA, ACNE AND SKIN DISORDER | MERCK & CO., INC. (US) | 1997-12-02 | — | — | US | disclosed |