Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 8/20 | 0.47 |
| ▸ | MAOA | P21397 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1232335 | 0.98 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL3346351 | 0.93 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| Hydrochloric Acid SCHEMBL28530836 | 0.92 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL11912907 | 0.88 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL8315263 | 0.86 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL3113016 | 0.86 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL8373486 | 0.86 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL8374769 | 0.86 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL8373505 | 0.86 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL8549614 | 0.86 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920014-B2 | Selective inhibition of bacterial topoisomerase I | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2018-03-20 | — | — | US | disclosed |
| US-20160229810-A1 | Selective Inhibition of Bacterial Topoisomerase I | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2016-08-11 | — | — | US | disclosed |
| WO-2015042438-A1 | SELECTIVE INHIBITION OF BACTERIAL TOPOISOMERASE I | THE FLORIDA INTERNATIONAL BOARD OF TRUSTEES MODESTO A. MAIDIQUE CAMPUS (US) | 2015-03-26 | — | — | WO | disclosed |
| US-5663042-A | LIGHT AND HEAT SENSITIVE SILVER HALIDE ELEMENNTS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-09-02 | — | — | US | disclosed |
| EP-0681210-A1 | Novel developing agents for (photo) thermographic systems | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-11-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160229810-A1 | Selective Inhibition of Bacterial Topoisomerase I | TOP1, TOP2B, TOP2A | ALDH1A1 3784/4885SMN1; SMN2 4650/4885LMNA 2277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.