Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TOP1 | P11387 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9210491 | 0.92 | KDM4E (0.40) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL7836509 | 0.90 | KCNH2 (0.46) | KDM4EHSD17B10ALDH1A1HPGDKCNH2 | |
| SCHEMBL7846922 | 0.90 | KCNH2 (0.46) | KDM4EHSD17B10ALDH1A1HPGDKCNH2 | |
| SCHEMBL7846924 | 0.90 | KCNH2 (0.46) | KDM4EHSD17B10ALDH1A1HPGDKCNH2 | |
| SCHEMBL7492274 | 0.90 | KDM4E (0.38) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL7494366 | 0.90 | KCNH2 (0.46) | KDM4EHSD17B10ALDH1A1HPGDKCNH2 | |
| SCHEMBL7836504 | 0.90 | KCNH2 (0.46) | KDM4EHSD17B10ALDH1A1HPGDKCNH2 | |
| SCHEMBL8925166 | 0.88 | CYP3A4 (0.39) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL8925167 | 0.88 | CYP3A4 (0.39) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL8922822 | 0.85 | ALDH1A1 (0.51) | KDM4EHSD17B10ALDH1A1HPGDKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5621105-A | REACTING HALO-SUBSTITUTED QUINOLONECARBOXYLIC ACID OR NAPHTHYRIDONECARBOXYLIC ACID WITH 1-AMINOMETHYL-2-OXA-7-AZABICYCLO/3.3.0/OCTANE | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-15 | — | — | US | disclosed |
| US-5574161-A | GRAMPOSITIVE BACTERICIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-12 | — | — | US | disclosed |
| EP-0589318-B1 | Antibacterial 7-(aminomethyl-oxa-7-azabicyclo(3.3.0)oct-7-yl)quinolone- and -naphthyridonecarboxylic acid derivatives | BAYER AG (DE) | 1995-11-15 | — | — | EP | disclosed |
| US-5395944-A | Bactericides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-03-07 | — | — | US | disclosed |
| EP-0589318-A2 | Antibacterial 7-(aminomethyl-oxa-7-azabicyclo(3.3.0)oct-7-yl)quinolone- and -naphthyridonecarboxylic acid derivatives | BAYER AG (DE) | 1994-03-30 | — | — | EP | disclosed |