Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8926496 | 0.92 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL7494369 | 0.90 | KCNH2 (0.37) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| SCHEMBL7496654 | 0.90 | KCNH2 (0.37) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| SCHEMBL7501610 | 0.90 | KCNH2 (0.37) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| SCHEMBL7492282 | 0.90 | KDM4E (0.31) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9209492 | 0.89 | CYP3A4 (0.31) | KCNH2 | |
| SCHEMBL9214867 | 0.86 | ALDH1A1 (0.42) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| Hydrochloric Acid SCHEMBL9210346 | 0.85 | KDM4E (0.45) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL7493085 | 0.85 | KCNH2 (0.45) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| SCHEMBL9274990 | 0.85 | KDM4E (0.44) | KDM4EALDH1A1HPGDHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520674-B1 | Antipsychotic benzodioxan derivatives | AMERICAN HOME PROD (US) | 1995-08-16 | — | — | EP | claimed |