Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 1/20 | 0.80 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 7/20 | 0.46 |
| ▸ | CA2 | P00918 | 7/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 5/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL49745 | 0.89 | HSPA5 (1.00) | HSPA5KEAP1TSHRHIF1ACYP2D6 | |
| SCHEMBL29357407 | 0.89 | HSPA5 (1.00) | HSPA5KEAP1TSHRHIF1ACYP2D6 | |
| SCHEMBL29839938 | 0.87 | HSPA5 (0.94) | HSPA5KEAP1TSHRHIF1ACYP2D6 | |
| SCHEMBL7809667 | 0.87 | HSPA5 (0.94) | HSPA5KEAP1TSHRHIF1ACYP2D6 | |
| SCHEMBL5852726 | 0.87 | HSPA5 (0.94) | HSPA5KEAP1TSHRHIF1ACYP2D6 | |
| Ammonia Solution, Strong SCHEMBL28323965 | 0.87 | HSPA5 (0.94) | HSPA5KEAP1TSHRHIF1ACYP2D6 | |
| SCHEMBL9307991 | 0.87 | HSPA5 (0.67) | HSPA5KEAP1TSHRHIF1ACYP2D6 | |
| Ethylene Glycol SCHEMBL28140490 | 0.82 | HSPA5 (0.84) | HSPA5KEAP1TSHRHIF1ACYP2D6 | |
| SCHEMBL30874252 | 0.80 | HSPA5 (0.80) | HSPA5KEAP1TSHRHIF1ACYP2D6 | |
| SCHEMBL5852506 | 0.80 | HSPA5 (0.80) | HSPA5KEAP1TSHRHIF1ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9255603-A | — | — | None | — | — | JP | disclosed |
| JP-H09255603-A | BIS(HIDROXYBENZYL)BIPHENYL AND ITS PRODUCTION | MEIWA KASEI KK | 1997-09-30 | — | — | JP | disclosed |