Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 11/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | STRADA | Q7RTN6 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8926780 | 0.82 | MAPK14 (0.51) | MAPK14MAOBMAPTGAAEGFR | |
| SCHEMBL14157006 | 0.79 | MAPK14 (0.49) | MAPK14MAOBNPC1LMNAMAPT | |
| SCHEMBL8924125 | 0.79 | ALDH1A1 (0.49) | MAPK14MAOBLMNAMAPTRAB9A | |
| SCHEMBL14157034 | 0.76 | MAOB (0.53) | MAPK14MAOBLMNAMAPTRAB9A | |
| SCHEMBL4123831 | 0.74 | DPP4 (0.51) | LMNAMAPTSMN1; SMN2GAA | |
| SCHEMBL25933615 | 0.73 | DPP4 (0.48) | NPC1MAPTRAB9APPARAGAA | |
| SCHEMBL20236380 | 0.73 | MAPT (0.45) | NPC1LMNAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL20772880 | 0.73 | MAOB (0.50) | MAPK14MAOBMAPTGAAEGFR | |
| SCHEMBL14156933 | 0.72 | MAOB (0.49) | MAPK14MAOBNPC1LMNAMAPT | |
| SCHEMBL5297104 | 0.72 | MAOB (0.51) | MAPK14MAOBLMNAMAPTPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639906-A | Fluorescent and NMR sensitive pH indicators | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1997-06-17 | — | — | US | disclosed |