Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 9/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8926641 | 0.82 | MAPK14 (0.48) | MAPK14MAOBMAPTGAAEGFR | |
| SCHEMBL14157006 | 0.82 | MAPK14 (0.49) | MAPK14MAOBKDM4EALDH1A1MAPT | |
| SCHEMBL27698512 | 0.82 | MAPK14 (0.56) | MAPK14MAOBPTGER1GSK3BBACE1 | |
| SCHEMBL8924125 | 0.81 | ALDH1A1 (0.49) | MAPK14MAOBKDM4EALDH1A1MAPT | |
| SCHEMBL14157034 | 0.79 | MAOB (0.53) | MAPK14MAOBALDH1A1MAPTGAA | |
| SCHEMBL1457756 | 0.75 | KDM4E (0.61) | KDM4EALDH1A1MAPTHPGDGLA | |
| SCHEMBL14156933 | 0.75 | MAOB (0.49) | MAPK14MAOBALDH1A1MAPTGAA | |
| SCHEMBL5297104 | 0.74 | MAOB (0.51) | MAPK14MAOBMAPTMRGPRX4FFAR4 | |
| SCHEMBL1495847 | 0.74 | LOXL2 (0.54) | KDM4EALDH1A1MAPTHPGDGLA | |
| Hydrochloric Acid SCHEMBL4418745 | 0.74 | MAPT (0.59) | KDM4EALDH1A1MAPTHPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639906-A | Fluorescent and NMR sensitive pH indicators | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1997-06-17 | — | — | US | disclosed |