Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9420060 | 0.77 | PRCP (0.40) | TRPA1KDM1AMAOAMAOBCHRNA7 | |
| SCHEMBL28874187 | 0.74 | TRPA1 (0.35) | TRPA1GAAAKR1C1POLB | |
| SCHEMBL7775220 | 0.71 | DDB1 (0.33) | USP2ALDH1A1MAPTSMN1; SMN2POLB | |
| SCHEMBL3401854 | 0.71 | DDB1 (0.39) | KDM1AMAOAMAOB | |
| SCHEMBL31504308 | 0.70 | TRPA1 (0.45) | TRPA1KDM1AMAOAMAOB | |
| SCHEMBL13430605 | 0.70 | FFAR3 (0.39) | CYP2C19MAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8890810 | 0.70 | FFAR3 (0.39) | CYP2C19MAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3711674 | 0.70 | USP2 (0.39) | CYP2C19USP2MAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL18801244 | 0.70 | TRPA1 (0.35) | TRPA1ALDH1A1KDM1AMAOAMAOB | |
| Hydrochloric Acid SCHEMBL28519862 | 0.68 | SLC18A3 (0.35) | USP2ALDH1A1MAPTSMN1; SMN2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624939-A | N-acyl pyrrolidines and drugs for the treatment or prevention of cholecystokinin and gastrin-related disorders | RHONE-POULENC RORER, S.A. (FR) | 1997-04-29 | — | — | US | disclosed |