Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15266660 | 0.91 | ALDH1A1 (0.33) | ALDH1A1ALOX15LMNABLMPMP22 | |
| SCHEMBL17905 | 0.91 | — | — | |
| Urea SCHEMBL4300103 | 0.88 | ALDH1A1 (0.40) | ALDH1A1ALOX15LMNABLMPMP22 | |
| Water SCHEMBL11338550 | 0.88 | — | — | |
| Methane SCHEMBL14973507 | 0.88 | — | — | |
| Propionic Acid SCHEMBL2197430 | 0.87 | FFAR3 (0.50) | ALDH1A1 | |
| SCHEMBL2825457 | 0.86 | — | — | |
| Methoxymethane SCHEMBL8591569 | 0.86 | ALOX15 (0.32) | ALOX15LMNABLMPMP22 | |
| Ethylene SCHEMBL8350667 | 0.85 | — | — | |
| Formaldehyde SCHEMBL4967135 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5622909-A | DEVELOPER LAYER COMPRISING LEUCO DYE, PHTHALIC ACID DERIVATIVE; STORAGE STABILITY | RICOH COMPANY, LTD. (JP) | 1997-04-22 | — | — | US | disclosed |