Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 6/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9060560 | 0.86 | CYP17A1 (0.46) | PDE2AEPHX2HCRTR1HCRTR2CACNA1H | |
| SCHEMBL12199925 | 0.86 | CYP17A1 (0.46) | PDE2AEPHX2HCRTR1HCRTR2CACNA1H | |
| SCHEMBL13557302 | 0.86 | PDE2A (0.44) | PDE2AEPHX2HCRTR1HCRTR2 | |
| SCHEMBL8225438 | 0.85 | SIGMAR1 (0.42) | — | |
| SCHEMBL22185629 | 0.85 | SLC6A4 (0.45) | PPARDPPARA | |
| SCHEMBL3158031 | 0.85 | CYP1A2 (0.41) | PDE2AEPHX2CACNA1HPPARD | |
| SCHEMBL14749509 | 0.84 | PDE2A (0.34) | PDE2AHCRTR1HCRTR2 | |
| SCHEMBL14749517 | 0.84 | KIF11 (0.35) | PDE2APPARDPPARA | |
| SCHEMBL14749522 | 0.84 | PPARD (0.36) | CACNA1HPPARDPPARA | |
| SCHEMBL6666327 | 0.83 | PDE2A (0.38) | PDE2AEPHX2HCRTR1HCRTR2CACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230157287-A1 | PESTICIDAL COMPOUNDS | BASF SE (DE) | 2023-05-25 | — | — | US | disclosed |
| US-20230137110-A1 | ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF | Beijing Summer Sprout Technology Co., Ltd. (CN) | 2023-05-04 | — | — | US | disclosed |
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |
| US-20220140252-A1 | NOVEL ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | Beijing Summer Sprout Technology Co., Ltd. (CN) | 2022-05-05 | — | — | US | disclosed |
| US-20220020935-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | Beijing Summer Sprout Technology Co., Ltd. (CN) | 2022-01-20 | — | — | US | disclosed |
| US-10428049-B2 | TRPA1 modulators | ALGOMEDIX, INC. (US) | 2019-10-01 | — | — | US | disclosed |
| US-20190016701-A1 | TRPA1 MODULATORS | ALGOMEDIX, INC. (US) | 2019-01-17 | — | — | US | disclosed |
| US-9951046-B2 | TRPA1 modulators | ALGOMEDIX, INC. (US) | 2018-04-24 | — | — | US | disclosed |
| US-9382258-B2 | Agents for treating pain and uses thereof | ABBVIE INC. (US) | 2016-07-05 | — | — | US | disclosed |
| US-9309260-B2 | Inhibitors of hepatitis C virus | PRESIDIO PHARMACEUTICALS, INC. (US) | 2016-04-12 | — | — | US | disclosed |
| US-20130302282-A1 | Inhibitors of Hepatitis C Virus | PRESIDIO PHARMACEUTICALS, INC. (US) | 2013-11-14 | — | — | US | disclosed |
| US-20130123262-A1 | NOVEL TRIAZINEDIONE DERIVATIVES AS GABAB RECEPTOR MODULATORS | ADDEX PHARMA S.A. (CH) | 2013-05-16 | — | — | US | disclosed |
| US-20130072471-A1 | Inhibitors of Ion Channels | MARRON BRIAN EDWARD (US) | 2013-03-21 | — | — | US | disclosed |
| US-8357711-B2 | Heterocyclic sulfonamides as inhibitors of ion channels | PFIZER LIMITED (GB) | 2013-01-22 | — | — | US | disclosed |
| US-20120251497-A1 | INHIBITORS OF HEPATITIS C VIRUS | PRESIDIO PHARMACEUTICALS, INC. | 2012-10-04 | — | — | US | disclosed |
| US-20120108595-A1 | PLATELET-ACTIVATING FACTOR RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME LLC | 2012-05-03 | — | — | US | disclosed |
| EP-1995241-B1 | Inhibitors of ion channels | ICAGEN INC (US) | 2010-03-17 | — | — | EP | disclosed |
| US-20090143358-A1 | INHIBITORS OF ION CHANNELS | ICAGEN, INC. (US) | 2009-06-04 | — | — | US | disclosed |
| EP-1995241-A1 | Inhibitors of ion channels | ICAgen, Incorporated (US) | 2008-11-26 | — | — | EP | disclosed |
| WO-2008118758-A1 | INHIBITORS OF ION CHANNELS | ICAGEN, INC. (GB) | 2008-10-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108595-A1 | PLATELET-ACTIVATING FACTOR RECEPTOR ANTAGONISTS | PTAFR, PAFAH1B2, PAFAH1B3 | PDE2A 1145/4885EPHX2 562/4885HCRTR1 2666/4885 |
| US-10428049-B2 | TRPA1 modulators | TRPA1, TRPV1, TRPV2 | PDE2A 883/4885EPHX2 1414/4885HCRTR1 204/4885 |
| US-20230137110-A1 | ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF | SLCO2B1, SLCO2A1, SLCO1B3 | PDE2A 2936/4885EPHX2 765/4885HCRTR1 4533/4885 |
| US-20130072471-A1 | Inhibitors of Ion Channels | TRPV1, TRPV5, TRPA1 | PDE2A 1677/4885EPHX2 1928/4885HCRTR1 1224/4885 |
| US-20230157287-A1 | PESTICIDAL COMPOUNDS | PNMT, CAT, DDT | PDE2A 242/4885EPHX2 1776/4885HCRTR1 472/4885 |
| US-20220140252-A1 | NOVEL ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | LEF1, PIEZO1, L1CAM | PDE2A 2795/4885EPHX2 1088/4885HCRTR1 4186/4885 |
| US-20190016701-A1 | TRPA1 MODULATORS | TRPA1, TRPV1, TRPV2 | PDE2A 883/4885EPHX2 1414/4885HCRTR1 204/4885 |
| US-20130302282-A1 | Inhibitors of Hepatitis C Virus | HAVCR2, LIPC, HCCS | PDE2A 2727/4885EPHX2 2505/4885HCRTR1 4010/4885 |
| US-20090143358-A1 | INHIBITORS OF ION CHANNELS | TRPV1, TRPV5, TRPA1 | PDE2A 1677/4885EPHX2 1928/4885HCRTR1 1224/4885 |
| US-20120251497-A1 | INHIBITORS OF HEPATITIS C VIRUS | HAVCR2, LIPC, HCCS | PDE2A 2727/4885EPHX2 2505/4885HCRTR1 4010/4885 |
| US-20220020935-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | OCIAD1, OCIAD2, LEF1 | PDE2A 4590/4885EPHX2 1703/4885HCRTR1 1799/4885 |
| US-20130123262-A1 | NOVEL TRIAZINEDIONE DERIVATIVES AS GABAB RECEPTOR MODULATORS | CHRNA5, GABRA5, GABRB3 | PDE2A 558/4885EPHX2 3179/4885HCRTR1 172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.