Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7029967 | 0.84 | KMT2A (0.52) | KMT2AMEN1CTNNB1IRAK4KDM4E | |
| SCHEMBL29728552 | 0.84 | KMT2A (0.52) | KMT2AMEN1CTNNB1IRAK4KDM4E | |
| SCHEMBL87637 | 0.78 | PTGS2 (0.57) | KDM4EHTTMAPTHSD17B10TSHR | |
| SCHEMBL29728528 | 0.77 | KMT2A (0.46) | KMT2AMEN1CTNNB1IRAK4KDM4E | |
| SCHEMBL3952526 | 0.76 | CA1 (0.59) | KMT2AKDM4EHTTMAPTTSHR | |
| SCHEMBL29463214 | 0.76 | GAA (0.50) | KMT2AMEN1CTNNB1KDM4EMAPT | |
| SCHEMBL32677394 | 0.76 | SMN1; SMN2 (0.49) | KMT2AMEN1CTNNB1IRAK4KDM4E | |
| SCHEMBL142738 | 0.76 | SMN1; SMN2 (0.49) | KMT2AMEN1CTNNB1IRAK4KDM4E | |
| SCHEMBL32677395 | 0.76 | SMN1; SMN2 (0.49) | KMT2AMEN1CTNNB1IRAK4KDM4E | |
| SCHEMBL140239 | 0.76 | GAA (0.50) | KMT2AMEN1CTNNB1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614498-A | OLIGOPEPTIDES, BRONCHDILATORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-03-25 | — | — | US | disclosed |
| US-5496928-A | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0555537-A2 | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-18 | — | — | EP | disclosed |