Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.38 |
| ▸ | SHBG | P04278 | 3/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8926937 | 0.83 | SRD5A2 (0.38) | ARKCNH2SRD5A2SHBGGPBAR1 | |
| SCHEMBL8926721 | 0.81 | PGR (0.31) | ARKCNH2LMNAPGR | |
| SCHEMBL8075347 | 0.81 | SHBG (0.51) | ARSRD5A2SHBGGPBAR1LMNA | |
| SCHEMBL8075351 | 0.81 | SHBG (0.51) | ARSRD5A2SHBGGPBAR1LMNA | |
| SCHEMBL8927033 | 0.79 | AR (0.36) | ARKCNH2SRD5A2SHBGGPBAR1 | |
| SCHEMBL8927275 | 0.78 | AR (0.37) | ARKCNH2SRD5A2GPBAR1CYP3A4 | |
| SCHEMBL8924896 | 0.78 | AR (0.35) | ARKCNH2SRD5A2SHBGGPBAR1 | |
| SCHEMBL8927180 | 0.77 | AR (0.36) | ARKCNH2SRD5A2 | |
| SCHEMBL8926795 | 0.77 | NR1H4 (0.36) | ARKCNH2SRD5A2HSD17B3 | |
| SCHEMBL8926946 | 0.76 | ESR1 (0.33) | ARKCNH2SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693809-A | PREGNANES FOR TREATING ALOPECIA, ACNE AND SKIN DISORDER | MERCK & CO., INC. (US) | 1997-12-02 | — | — | US | disclosed |