Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glycinebetaine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT2 | P23786 | 1/20 | 0.41 |
| ▸ | CPT1A | P50416 | 1/20 | 0.41 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | SLC25A20 | O43772 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL525540 | 0.87 | ALDH1A1 (0.49) | ALDH1A1DNM1HRH3HSP90AA1FAAH | |
| SCHEMBL10393971 | 0.87 | ALDH1A1 (0.49) | ALDH1A1DNM1HRH3HSP90AA1FAAH | |
| Glycinebetaine SCHEMBL9263534 | 0.83 | CPT2 (0.36) | CPT2CPT1ACPT1BDNM1 | |
| Stearic Acid SCHEMBL12544816 | 0.75 | GPR84 (0.41) | ALDH1A1CYP2D6TSHRMEN1KMT2A | |
| Palmitic Acid SCHEMBL12544931 | 0.75 | GPR84 (0.41) | ALDH1A1CYP2D6TSHRMEN1KMT2A | |
| Dodecanoate SCHEMBL20183472 | 0.75 | GPR84 (0.41) | ALDH1A1CYP2D6TSHRMEN1KMT2A | |
| Myristic Acid SCHEMBL12545069 | 0.75 | GPR84 (0.41) | ALDH1A1CYP2D6TSHRMEN1KMT2A | |
| Decanoic Acid SCHEMBL8774854 | 0.71 | GPR84 (0.63) | ALDH1A1TSHRMEN1KMT2AMAPT | |
| Stearic Acid SCHEMBL3245114 | 0.71 | GPR84 (0.63) | ALDH1A1TSHRMEN1KMT2AMAPT | |
| Dodecanoate SCHEMBL3249425 | 0.71 | GPR84 (0.63) | ALDH1A1TSHRMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022259877-A1 | COSMETIC PREPARATION | 株式会社 資生堂 | 2022-12-15 | — | — | WO | disclosed |
| US-5676938-A | MIXTURES CONTAINING POLYSILOXANES AND HAVING STABILITY, WATER REPELLENCY AND SMOOTH FEEL ON THE SKIN | TOSHIBA SILICONE CO., LTD. (JP) | 1997-10-14 | — | — | US | disclosed |
| EP-0590192-B1 | Cosmetic composition | TOSHIBA SILICONE (JP) | 1996-12-04 | — | — | EP | disclosed |
| EP-0590192-A1 | Cosmetic composition | TOSHIBA SILICONE CO., LTD. (JP) | 1994-04-06 | — | — | EP | disclosed |